Advances in Electrophysiological Research
نویسندگان
چکیده
Electrophysiological measures of brain function are effective tools to understand neurocognitive phenomena and sensitive indicators of pathophysiological processes associated with various clinical conditions, including alcoholism. Individuals with alcohol use disorder (AUD) and their high-risk offspring have consistently shown dysfunction in several electrophysiological measures in resting state (i.e., electroencephalogram) and during cognitive tasks (i.e., event-related potentials and event-related oscillations). Researchers have recently developed sophisticated signal-processing techniques to characterize different aspects of brain dynamics, which can aid in identifying the neural mechanisms underlying alcoholism and other related complex disorders.These quantitative measures of brain function also have been successfully used as endophenotypes to identify and help understand genes associated with AUD and related disorders. Translational research also is examining how brain electrophysiological measures potentially can be applied to diagnosis, prevention, and treatment.
منابع مشابه
Electrophysiological Study of Sciatic Nerve Regeneration Through Tubes Seeded with Schwann Cells
A B S T R A C TIntroduction: Peripheral nerve injury is a common disorder and leads to permanent neurological defects. Schwann cells have been shown to have nerve repair after being transplanted in peripheral nerve injury. The aim of this study was to determine the beneficial effect of allograft Schwann cells on electrophysiological outcome after transection of the sciatic nerve in rats.Methods...
متن کاملThe state dependency effect of morphine on memory by behavioral and electrophysiological methods in freely moving rats
Endogenous opioid system agonists exert amnestic effects in different models of memory. It has been suggested that these amnestic effects may be linked indirectly to state-dependent learning. Accordingly pre-training administration of morphine can impair the retrieval of learned tasks in a state dependent manner, which is reversible by pre test morphine administration. In this study, state depe...
متن کاملThe state dependency effect of morphine on memory by behavioral and electrophysiological methods in freely moving rats
Endogenous opioid system agonists exert amnestic effects in different models of memory. It has been suggested that these amnestic effects may be linked indirectly to state-dependent learning. Accordingly pre-training administration of morphine can impair the retrieval of learned tasks in a state dependent manner, which is reversible by pre test morphine administration. In this study, state depe...
متن کاملUncovering the visual “alphabet”: Advances in our understanding of object perception
The ability to rapidly and accurately recognize visual stimuli represents a significant computational challenge. Yet, despite such complexity, the primate brain manages this task effortlessly. How it does so remains largely a mystery. The study of visual perception and object recognition was once limited to investigations of brain-damaged individuals or lesion experiments in animals. However, i...
متن کاملElectrophysiological study of amygdale-induced changes in the excitability of CA1 hippocampal pyramidal neurons in male adult rats
Introduction: Many studies have shown that amygdala kindling produces synaptic potentiation by induction of changes in the neuronal electrophysiological properties and inward currents both in epileptic focus and in the areas which are in connection with the epileptic focus and have important role in seizure development and progression such as hippocampal CA1 region. However, cellular mechani...
متن کامل